Publication
- F Amiri, AA Akinpelu, WC Keith, ... C. Wang, P. Chen, p. Mistriotis, " Confinement controls the directional cell responses to fluid forces," Cell reports 43, 114692, September 24, 2024.
- X. Kang, N Mita, L Zhou, S Wu,Z Yue, R. Babu*, P. Chen*, " Nanotechnology in Advancing Chimeric Antigen Receptor T Cell Therapy for Cancer Treatment," Pharmaceutics. 2024, 16(9), 1228.
- W. Yang, Z. Zhang, C. Ma, Z. Gu, M. Witkowski, Y. Tian, E. A. Lipke, F. Ding, I. Aifantis, W. Chen, and P. Chen, "Nanoplasmonic Mapping of Single-Cell Cytokine Secretomic Signatures in CAR T-Cell Cancer Therapy," (in submission).
- J. He, S. Wu, W. Chen, A. Kim, W. Yang, C. Wang, Z. Gu, J. Shen, S. Dai, W. Chen, and P. Chen*, " Calligraphy of Nanoplasmonic Bioink-Based Multiplex Immunosensor for Precision Immune Monitoring and Modulation," ACS Appl. Mater. Interfaces (2023).
- M. Annaji, N. Mita, J. Heard, X. Kang, I. Poudel, O. Fasina, P. Baskaran, S. Boddu, A. Tiwar, P. Chen, C. Lyman, R. Babu *, " 3D‑Printed Capsaicin‑Loaded Injectable Implants for Targeted Delivery in Obese Patients," AAPS PharmSciTech (2023) 24:200.
- B. Ma, X. Liu, Z. Zhang, C. Ma, R. Chand, S. Patwardhan, C. Wang, S. Thamphiwatana, P. Chen, W. Chen*, " A digital nanoplasmonic microarray immunosensor for multiplexed cytokine monitoring during CAR T-cell therapy from a leukemia tumor microenvironment model," Biosens. Bioelectron. 230 (2023), 115247.
- F. Antony, X. Kang, C. Pundkar, C. Wang, A. Mishra, P. Chen, R. Babu, A. Suryawanshi *, " Targeting β-catenin using XAV939 nanoparticle promotes immunogenic cell death and suppresses conjunctival melanoma progression," International Journal of Pharmaceutics. 640 (2023), 123043.
- C. Pundkar, F. Antony, X. Kang, A. Mishra, R. Babu, P. Chen, F. Li, A. Suryawanshi *, " Targeting Wnt/β-catenin signaling using XAV939 nanoparticles in tumor microenvironment-conditioned macrophages promote immunogenicity," Heliyon. 9 (2023), e16688.
- X. Kang, S. Jadhav, M. Annaji, C. Huang, R. Amin, J. Shen, C. Ashby Jr, A. Tiwari, R. Babu*, P. Chen*, " Advancing Cancer Therapy with Copper/Disulfiram Nanomedicines and Drug Delivery Systems," Pharmaceutics. 2023, 15(6), 1567.
- X. Kang, Qi Wang, Siqi Wu, C. Wang, M. Annaji, C. Huang, J. Shen, P. Chen*, R. Babu* " Liposomal DQ in Combination with Copper Inhibits ARID1A Mutant Ovarian Cancer Growth," Biomolecules. 2023, 13(5), 744.
- L. Zhou, L. Liu, M. Chang, C. Ma, W. Chen, P. Chen*, "’Spatiotemporal dissection of tumor microenvironment via in situ sensing and monitoring in tumor-on-a-chip," Biosens. Bioelectron. 225 (2023), 115061.
- J. He, L. Zhou, G. Huang, J. Shen, W. Chen, C. Wang, A. Kim, Z. Zhang, W. Chen, S. Dai, F. Ding*, and P. Chen*, "Enhanced Label-Free Nanoplasmonic Cytokine Detection in SARS-CoV 2 Induced Inflammation Using Rationally Designed Peptide Aptamer," ACS Appl. Mater. Interfaces (2022).
- X. Kang, J. Wang, C. Huang, F. Wibowo, R. Amin, P. Chen, F. Li*, "Diethyldithiocarbamate Copper Nanoparticle Overcomes Resistance in Cancer Therapy without Inhibiting P-glycoprotein," Nanotechnol. Biol. Med. (2022).
- J. Shen, Z. Zheng, T. Dinh, C. Wang, M. Chen, P. Chen, Q. Ma, P. Herrero, L. Kang, S. Dai*, "Hyperbolic Phonon Polaritons with Positive and Negative Phase Velocities in Suspended α-MoO3," Appl. Phys. Lett. 120 (2022), 113101.
- Z. Gao*, C. Wang, J. He, P. Chen*, "Pd@Pt Nanodendrites as Peroxidase Nanomimics for Enhanced Colorimetric ELISA of Cytokines with Femtomolar Sensitivity," Chemosensors 10 (2022), 359.
- Z. Gao, Y. Song, T. Y. Hsiao, J. He, C. Wang, J. Shen, A. MacLachlan, S. Dai, B. H. Singer, K. Kurabayashi*, and P. Chen*, "Machine-Learning-Assisted Microfluidic Nanoplasmonic Digital Immunoassay for Cytokine Storm Profiling in COVID-19 Patients," ACS Nano 15 (2021), 18023.
- C. Wang, C. Huang, Z. Gao, J. Shen, J. He, A. MacLachlan, C. Ma, Y. Chang, W. Yang, Y. Cai, Y. Lou, S. Dai, W. Chen, F. Li*, and P. Chen*, "Nanoplasmonic Sandwich Immunoassay for Tumor-Derived Exosome Detection and Exosomal PD-L1 Profiling," ACS Sensors 6 (2021), 3308.
- X. Kang, Y. Cai, Q. Wang, C. Wang, W. Chen, W. Yang, A.Suryawanshi, G. Zhou, P. Chen, and F. Li*, "Near-Infrared Light Triggered Activation of Pro-Drug Combination Cancer Therapy and Induction of Immunogenic Cell Death," International Journal of Pharmaceutics 607 (2021), 120972.
- M. K. Brahma, E. H. Gilglioni, L. Zhou, E. Trepo, P. Chen, and E. N. Gurzov, "Oxidative Stress in Obesity-associated Hepatocellular Carcinoma: Sources, Signaling and Therapeutic Challenges," Oncogene (2021), 1-13.
- S. Du, I. Chen, A. MacLachlan, Y. Liu, T. Huang, Z. Cheng, P. Chen*, and B. A. Chin, "3D Phage-based Biomolecular Filter for Effective High Throughput Capture of Salmonella Typhimurium in Liquid Streams," Food Research International (2021), 110181.
- P. Chen, F. Ding, R. Cai, I. Javed, W. Yang, Z. Zhang, Y. Li, T. P. Davis, P. C. Ke, and C. Chen, "Amyloidosis Inhibition, a New Frontier of the Protein Corona," Nano Today , 35 (2020), 100937.
- C. Wang, Y. Cai, A. MacLachlan, and P. Chen*, "Novel Nanoplasmonic Structure based Integrated Microfluidic Biosensors for Label-Free in Situ Immune Functional Analysis," IEEE Nanotechnology Magazine 14(2020),46-C3.
- W. Yang, H. Veroniaina, X. Qi*, P. Chen*, F. Li*, and P. C. Ke, "Soft and Condensed Nanoparticles and Nanoformulations for Cancer Drug Delivery and Repurpose," Advanced Theraputics 3 (2020), 1900102.
- A. Faridi, W. Yang, H. G. Kelly, C. Wang, T. P. Davis*, P. Chen*, S. J. Kent*, and P. C. Ke*, "Differential Roles of Plasma Protein Corona on Immune Cell Association and Cytokine Secretion of Oligomeric and Fibrillar Beta-Amyloid," Biomacromolecules 20 (2019), 4208.
- Y. Chang, J. Jiang, W. Chen, W. Yang, L. Chen, P. Chen, J. Shen, S. Qian, T. Zhou, L. Wu, L. Hong, Y. Huang*, and F. Li*, "Biomimetic Metal-Organic Nanoparticles Prepared with a 3D-Printed Microfluidic Device as a Novel Formulation for Disulfiram-based Therapy Against Breast Cancer," Applied Materials Today (2019), 100492.
- Y. Cai, J. Zhu, J. He, W. Yang, C. Ma, F. Xiong, F. Li, W. Chen and P. Chen,"Magnet Patterned Superparamagnetic Fe3O4/Au Core-Shell Nanoplasmonic Sensing Array for Label-Free High Throughput Cytokine Immunoassay," Adv. Healthc. Mater 8 (2019), 1801478.
- I. Javed, J. He, A. Kakinen, A. Faridi, W. Yang, T. P. Davis, P. C. Ke, and P. Chen,"Probing the Aggregation and Immune Response of Human Islet Amyloid Polypeptide with Ligand-Stabilized Gold Nanoparticles," ACS Appl. Mater. Interfaces 11 (2019), 10462.
- W. Chen, W. Yang, P. Chen, Y. Huang, and F. Li, "Disulfiram Copper Nanoparticles Prepared with a Stabilized Metal Ion Ligand Complex Method for Treating Drug-Resistant Prostate Cancers," ACS Appl. Mater. Interfaces. 10 (2018), 41118.
- J. Y. Zhu, J. He, M. Verano, A. T. Brimmo, A. Glia, M. A. Qasaimeh, P. Chen, J. O. Aleman and W. Chen, "An Integrated Adipose-Tissue-On-Chip Nanoplasmonic Biosensing Platform for Investigating Obesity-associated Inflammation," Lab on a Chip. 18 (2018), 3550.
- J. He, A. T. Brimmo, M. A. Qasaimeh, P. Chen, and W. Chen, "Recent Advances and Perspectives in Microfluidics-Based Single-Cell Biosensing Techniques," Small Methods 1 (2017), 1700192.
- X. W. Ge, A. Kakinen, E. N. Gurzov, W. Yang, L. Pang, E. H. Pilkington, P. Nedumpully-Govindan, P. Chen, F. Separovic, T. P. Davis, P. C. Ke, and F. Ding, "Zinc-Coordination and C-Peptide Complexation: A Mechanism for the Native Inhibition of IAPP Aggregation," Chem. Comm. 53 (2017), 9394. (Featured as front cover)
- Y. J. Song*, P. Chen*, M. T. Chuang, R. Nidetz, Y. Park, Z. H. Liu, W. McHugh, T. T. Cornell, J. Fu, and K. Kurabayashi, "AC Electroosmosis-Enhanced Nano-Plasmofluidic Detection of Ultra-Low-Concentration Cytokine," Nano Lett. 17 (2017), 2374. (* equal contribution)
- B. Ryu, H. Nam, B. R. Oh, Y. Song, P. Chen, Y. Park, W. Wan, K. Kurabayashi, and X. Liang, "Cyclewise Operation of Printed MoS2 Transistor Biosensors for Rapid Biomolecule Quantification at Femtomolar Levels," ACS Sensors 2 (2017), 274.
- B. R. Oh, P. Chen, R. Nidetz, W. McHugh, J. Fu, T. P. Shanley, T. T. Cornell, and K. Kurabayashi, "Multiplexed Nanoplasmonic Temporal Profiling of T-Cell Response under Immunomodulatory Agent Exposure," ACS Sensors 1 (2016), 941.
- E. N. Gurzov, B. Wang, E. H. Pilkington, P. Chen, A. Kakinen, W. J. Stanley, S. A. Litwak, E. G. Hanssen, T. P. Davis, F. Ding, and P. C. Ke, "Inhibition of hIAPP Amyloid Aggregation and Pancreatic beta-Cell Toxicity by OH-Terminated PAMAM Dendrimer," Small 12 (2016), 1615.
- P. N. Govindan, E. N. Gurzov, P. Chen, E. H. Pilkington, W. J. Stanley, S. A. Litwak, T. P. Davis, P. C. Ke, and F. Ding, "Graphene Oxide Inhibits hIAPP Amyloid Fibrillation and Toxicity in Insulin-Producing NIT-1 Cells," Phys. Chem. Chem. Phys. 18 (2016), 94.
- M. Chen, H. Nam, H. Rokni, S. Wi, J. S. Yoen, P. Chen, K. Kurabayashi, W. Lu, and X. Liang, "Nanoimprint-Assisted Shear Exfoliation (NASE) for Producing Multilayer Transition Metal Dichalcogenide Device Arrays," ACS Nano 9 (2015), 8773.
- P. Chen, N.-T. Huang, M. T. Chuang, T. T. Cornell, and K. Kurabayashi, "Label-free Cytokine Micro- and Nano-biosensing towards Personalized Medicine of Systemic Inflammatory Disorders," Adv. Drug Deliv. Rev. 95 (2015), 90.
- P. Chen, M. T. Chung, W. McHugh, R. Nidetz, Y. Li, J. Fu, T. T. Cornell, T. P. Shanley, and K. Kurabayashi, "Multiplex Serum Cytokine Immunoassay Using Nanoplasmonic Biosensor Microarrays," ACS Nano 9 (2015), 4173. (Featured by GenomeWeb, MICHR; Highlighted in Integrative Biology)
- B. Wang, S. A. Seabrook, P. Nedumpully-Govindan, P. Chen, H. Yin, L. Waddington, V. C. Epa, D. A. Winkler, J. K. Kirby, F. Ding, and P. C. Ke, "Thermostability and Reversibility of Silver Nanoparticle-Protein Binding," Phys. Chem. Chem. Phys. 17 (2015), 1728.
- H. Nam, B.-R. Oh, P. Chen, J. S. Yoen, S. Wi, M. Chen, K. Kurabayashi, and X. Liang, "Two Different Device Physics Principles for Operating MoS2 Transistor Biosensors with Femtomolar-Level Detection Limits," Appl. Phys. Lett. 107 (2015), 012105.
- H. Nam, B.-R. Oh, P. Chen, M. Chen, S. Wi, W. Wan, K. Kurabayashi, and X. Liang, "Multiple MoS2 Transistors for Sensing Molecule Interaction Kinetics," Sci. Rep. 5 (2015), 10546.
- P. Chen, S. A. Seabrook, V. C. Epa, J. Newman, K. Kurabayashi, A. S. Barnard, D. A. Winkler, J. K. Kirby, and P. C. Ke, "Contrasting Effects of Nanoparticle Binding on Protein Denaturation," J. Phys. Chem. C 118 (2014), 22069.
- B.-R. Oh, N.-T. Huang, W. Chen, J. H. Seo, P. Chen, T. T. Cornell, T. P. Shanley, J. Fu, and K. Kurabayashi, "Integrated Nanoplasmonic Sensing for Cellular Functional Immunoanalysis Using Human Blood," ACS Nano 8 (2014), 2667.
- Y. Wen, N. K. Geitner, R. Chen, F. Ding, P. Chen, R. E. Andorfer, P. N. Govindan, and P. C. Ke, "Binding of Cytoskeletal Proteins with Silver Nanoparticles," RSC Adv. 3 (2013), 22002.
- R. Li, R. Chen, P. Chen, Y. Wen, P. C. Ke, and S. S. Cho, "Computational and Experimental Characterizations of Silver Nanoparticle-Apolipoprotein Biocorona," J. Phys. Chem. B, 117 (2013), 43.
- S. Radic, N. K. Geitner, R. Podila, A. Kakinen, P. Chen, P. C. Ke, and F. Ding, "Competitive Binding of Natural Amphiphiles with Graphene Derivatives," Sci. Rep. 3 (2013), 2273.
- A. Kakinen, F. Ding, P. Chen, M. Mortimer, A. Kahru, and P. C. Ke, "Interaction of Firefly Luciferase and Silver Nanoparticles and Its Imapct on Enzyme Activity," Nanotechnology, 24 (2013), 34.
- F. Ding, S. Radic, R. Chen, P. Chen, N. K. Geitner, J. M. Brown, and P. C. Ke*, "Direct Observation of a Single Nanoparticle-Ubiquitin Corona Formation," Nanoscale 5 (2013), 9162.
- R. N. Urankar, R. M. Lust, E. Mann, P. Katwa, X. Wang, R. Podila, S.C. Hilderbrand, B. S. Harrison, P. Chen, P. C. Ke, A. M. Rao, J. M. Brown and C. J. Wingard, "Expansion of Cardiac Ischemia/Reperfusion Injury After Instillation of Three Forms of Multi-Walled Carbon Nanotubes," Part. Fibre Toxicol. 9 (2012), 38.
- P. Chen, B. Powell, M. Mortimer, and P. C. Ke, "Adaptive Interactions between Zinc Oxide Nanoparticles and Chlorella sp." Environ. Sci. Technol. 46 (2012), 12178.
- P. Bhattacharya, S. H. Kim, P. Chen, R. Chen, A. M. Spuches, J. M. Brown, M. H. Lamm, and P. C. Ke, "Dendrimer-Fullerenol Soft-Condensed Nanoassembly," J. Phys. Chem. C 116 (2012), 15775.
- X. Wang, P. Katwa, R. Podila, P. Chen, P.C. Ke, A. M. Rao, D. M. Walters, C. J. Wingard, and J. M. Brown, "Multi-Walled Carbon Nanotube Instillation Impairs Pulmonary Function in C57BL/6 Mice," Part. Fibre Toxicol. 8 (2011), 24.
- P. Chen, Y. Yang, P. Bhattacharya, P. Wang, and P. C. Ke, "A Tris-Dendrimer for Hosting Diverse Chemical Species," J. Phys. Chem.
C 115 (2011), 12789.
- K. Lingam, R. Podila, C. Loebick, P. Chen, P. C. Ke, B. Powell, L. Pfefferle and A. M. Rao, "Effect of Bundling on the Pi-Plasmon Energy in Sub-Nanometer Single Walled Carbon Nanotubes," Carbon 49 (2011), 3803.
- I. Huizar, A. Malur, Y. A. Midgette, C. Kukoly, P. Chen, P. C. Ke, R. Podia, A. M. Rao, C. J. Wingard, L. Dobbs, B. P. Barna, M. S. Kavuru, and M. J. Thomassen, "Novel Murine Model of Chronic Granulomatous Lung Inflammation Elicited by Carbon Nanotubes," Am. J. Respir. Cell Mol. Biol. 45 (2011), 858.
- R. Podila, P. Chen, J. Reppert, A. M. Rao, and P. C. Ke, "Biomolecular Sensing Using Gold Nanoparticle-Coated ZnO Nanotetrapods," J Mater. Research 26 (2011), 2328.
- P. Bhattacharya, P. Chen, M. N. Spano, L. Zhu, and P. C. Ke, "Copper Detection Utilizing Dendrimer and Gold Nanowire-Induced Surface Plasmon Resonance," J.
Appl. Phys. 109 (2011), 014911.
- P. Chen, Q. Gan, F. Bartoli, and L. Zhu, "Spoof Surface Plasmon Assisted Light Beaming in Mid-infrared," J. Opt. Soc. Am. B 27, (2010) 685.
- P. Chen, Q. Gan, F. Bartoli, and L. Zhu, "Near Field Resonance Enhanced Plasmonic Light Beaming,"
IEEE Photonics
J. 2, (2010) 8.
©2021 - Penyu Chen at Auburn University