Pathology and Pathogenesis (page 402)
Cause: Nucleation and precipitation of salts in renal structures
Contributing Factors
- Dehydration: Less salt “dissolved”
- High protein diets: Acidosis and Inc GFR: Ca
- High sodium diet: Calcium oxalate
- Essential Hypertension: Hypercalciuria
Dietary calcium and oxalate does not enhance likelihood of stone formation in most patients